Phospho-IKB alpha (Ser36) Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Product Specifications
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Synonyms
IKB alpha (phospho S36) ; p-IKB alpha (phospho S36) ; I kappa B alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; IKBA_HUMAN; IKBalpha; MAD 3; MAD3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappa-B inhibitor alpha; NFKBI; NFKBIA; Nuclear factor of kappa light chain gene enhancer in B cells; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha.
Gene ID
4792
Swiss Prot
P25963
Modification Site
Ser36
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Phospho-IKB alpha (Ser36)
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic peptide derived from human phospho-IKB alpha (Ser36)
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat, Cow, Sheep, Pig, Rabbit
Gene ID URL
4792
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6158735-01 0.1 mL
MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1) (PE)
Ask
View Details 
MBS6158735-02 5x 0.1 mL
MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1) (PE)
Ask
View Details 
MBS6303822-01 0.2 mL
GPR171, CT (GPR171, H963, Probable G-protein coupled receptor 171, G-protein coupled receptor H963) (APC)
Ask
View Details MBS6303822-02 5x 0.2 mL
GPR171, CT (GPR171, H963, Probable G-protein coupled receptor 171, G-protein coupled receptor H963) (APC)
Ask
View Details 