GLK Polyclonal Antibody

Product Specifications

Background

Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

Synonyms

GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-4; Hexokinase-D; GCK

Gene ID

2645

Swiss Prot

P35557

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

101-200/465

Target

GLK

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GCK

Applications

WB, ELISA, FCM, IHC-P

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Mouse, Dog, Pig, Horse, Chicken, Rabbit

Gene ID URL

2645

Isotype

IgG

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