GATA4 Polyclonal Antibody
Product Specifications
Background
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP) -mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Synonyms
TOF; ASD2; VSD1; TACHD; Transcription factor GATA-4; GATA-binding factor 4; GATA4
Gene ID
2626
Swiss Prot
P43694
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
261-360/442
Target
GATA4
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GATA-4
Applications
WB, ELISA, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Specificity
May also interact with GATA-5, GATA-6
Prediction Reactivity
Human, Rat, Dog, Cow, Pig, Chicken, Rabbit
Gene ID URL
2626
Isotype
IgG
Curated Selection
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