FDC-SP Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation.
Synonyms
FDC; FDCs; Follicular dendritic cell; Follicular dendritic cell secreted protein; Follicular dendritic cell; Follicular dendritic cell secreted peptide; FDC secreted protein.
Gene ID
494224
Swiss Prot
Q5R1M6
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
17-81/81
Target
FDC-SP
Clonality
Polyclonal
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from rat FDC-SP
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1ug/ul
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-1766R-APC
Prediction Reactivity
Human, Rat, Horse
Gene ID URL
494224
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6346549-01 0.2 mL
SF3B3, CT (SF3B3, KIAA0017, SAP130, Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130kD subunit, STAF130, Spliceosome-associated protein 130) (APC)
Ask
View Details 
MBS6346549-02 5x 0.2 mL
SF3B3, CT (SF3B3, KIAA0017, SAP130, Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130kD subunit, STAF130, Spliceosome-associated protein 130) (APC)
Ask
View Details 
ARP54406_P050-FITC 100 µL
C10orf132 Antibody - N-terminal region : FITC (ARP54406_P050-FITC)
Ask
View Details MBS1314317-01 0.02 mg (E-Coli)
Recombinant Arabidopsis thaliana Chaperone protein dnaJ 20, chloroplastic (ATJ20)
Ask
View Details MBS1314317-02 0.1 mg (E-Coli)
Recombinant Arabidopsis thaliana Chaperone protein dnaJ 20, chloroplastic (ATJ20)
Ask
View Details 
MBS1314317-03 0.02 mg (Yeast)
Recombinant Arabidopsis thaliana Chaperone protein dnaJ 20, chloroplastic (ATJ20)
Ask
View Details