E2F3 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity) .

Synonyms

E2F-3; Transcription factor E2F3; E2F3; KIAA0075

Gene ID

1871

Swiss Prot

O00716

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

381-465/465

Target

E2F3

Clonality

Polyclonal

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human E2F3

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Rabbit

Gene ID URL

1871

Isotype

IgG

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