XBP1 Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR) . Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) . Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N (3) [AT]T-3', and also to some TPA response elements (TRE) . Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
Synonyms
XBP2; TREB5; XBP-1; X-box-binding protein 1; Tax-responsive element-binding protein 5; XBP1
Gene ID
7494
Swiss Prot
P17861
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
51-150/261
Target
XBP1
Clonality
Polyclonal
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human XBP-1
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
XBP-1 antibody will recognize both isoforms, may also interact with chicken
Prediction Reactivity
Cow, Chicken
Gene ID URL
7494
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
