XBP1 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR) . Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) . Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N (3) [AT]T-3', and also to some TPA response elements (TRE) . Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Synonyms

XBP2; TREB5; XBP-1; X-box-binding protein 1; Tax-responsive element-binding protein 5; XBP1

Gene ID

7494

Swiss Prot

P17861

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

51-150/261

Target

XBP1

Clonality

Polyclonal

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human XBP-1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

XBP-1 antibody will recognize both isoforms, may also interact with chicken

Prediction Reactivity

Cow, Chicken

Gene ID URL

7494

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx887652-01 10 nmol

Human hsa-miR-6871-5p miRNA Antagomir

Ask

View Details

abx887652-02 20 nmol

Human hsa-miR-6871-5p miRNA Antagomir

Ask

View Details

MBS7195815 Inquire

Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) camk2d2 Polyclonal Antibody

Ask

View Details

MBS6349564-01 0.2 mL

SNX2, CT (SNX2, Sorting nexin-2, Transformation-related gene 9 protein) (Biotin)

Ask

View Details

MBS6349564-02 5x 0.2 mL

SNX2, CT (SNX2, Sorting nexin-2, Transformation-related gene 9 protein) (Biotin)

Ask

View Details

QP8015-ec-200ug 200ug

Recombinant S. aureus Staphylococcal secretory antigen ssaA2 Protein, His-SUMO, E.coli-200ug

Ask

View Details