Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-STAT3 (Tyr705) Polyclonal Antibody

Product Specifications

Background

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) .

Synonyms

APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3

Gene ID

6774

Swiss Prot

P40763

Modification Site

Tyr705

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Chicken

Target

Phospho-STAT3 (Tyr705)

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6774

Isotype

IgG

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Neuropeptide S (Mouse) TFA
orb1981507-01 5 mg

Neuropeptide S (Mouse) TFA

Sign In for Pricing
View Details
Neuropeptide S (Mouse) TFA
orb1981507-02 50 mg

Neuropeptide S (Mouse) TFA

Sign In for Pricing
View Details
GENLISA™ Bovine Interleukin 22 (IL22) ELISA
KLB2356 1x 96 Well

GENLISA™ Bovine Interleukin 22 (IL22) ELISA

Sign In for Pricing
View Details
PLEKHN1 Recombinant Protein (Mouse)
RP162881 100 µg

PLEKHN1 Recombinant Protein (Mouse)

Sign In for Pricing
View Details
Recombinant Human SHC4 Protein - (Dry Ice)
H00399694-P01-25ug 25 µg

Recombinant Human SHC4 Protein - (Dry Ice)

Sign In for Pricing
View Details
MST1R (macrophage Stimulating 1 Receptor (c-met-Related Tyrosine Kinase), CD136, CDw136, PTK8, RON) (MaxLight 650)
MBS6228804-01 0.1 mL

MST1R (macrophage Stimulating 1 Receptor (c-met-Related Tyrosine Kinase), CD136, CDw136, PTK8, RON) (MaxLight 650)

Sign In for Pricing
View Details