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Phospho-STAT1 (Tyr701) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

Synonyms

STAT1Tyr701; signal transducers and activators of transcription 1; DKFZp686B04100; ISGF 3; Phosphorylated Stat1pTyr701; Signal transducer and activator of transcription 1 91kDa; Signal transducer and activator of transcription 1 alpha/beta; STAT 1; STAT 91; STAT91; Transcription factor ISGF 3 components p91 p84.

Gene ID

6772

Modification Site

Tyr701

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Phospho-STAT1 (Tyr701)

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1ug/ul

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Rat, Dog, Cow, Sheep, Pig, Rabbit

Gene ID URL

6772

Isotype

IgG

Curated Selection

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