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CD7 Polyclonal Antibody

Product Specifications

Background

CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.

Synonyms

GP40; TP41; Tp40; LEU-9; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; CD7

Gene ID

924

Swiss Prot

P09564

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

181-240/240

Target

CD7

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CD7

Applications

ELISA, FCM, IHC-P

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

924

Isotype

IgG

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