CSB Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Product Specifications
Background
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX (ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Synonyms
CSB; CKN2; COFS; ARMD5; COFS1; RAD26; UVSS1; DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB; ERCC6
Gene ID
2074
Swiss Prot
Q03468
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
201-300/1493
Target
CSB
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic peptide derived from human ERCC6
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Mouse
Gene ID URL
2074
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
32041-05171 5x 30 µg
Human Apolipoprotein C-I (Apo C1) AssayLite™ Antibody (PerCP Conjugate)
Ask
View Details 
MBS7039617-01 0.02 mg
Recombinant Rhodopseudomonas palustris UPF0314 protein RPA0307 (RPA0307)
Ask
View Details 
MBS7039617-02 0.1 mg
Recombinant Rhodopseudomonas palustris UPF0314 protein RPA0307 (RPA0307)
Ask
View Details MBS7039617-03 5x 0.1 mg
Recombinant Rhodopseudomonas palustris UPF0314 protein RPA0307 (RPA0307)
Ask
View Details