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P73 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Synonyms

P73; Tp73; TAp73; Tumor protein p73; p53-like transcription factor; p53-related protein; Trp73

Gene ID

22062

Swiss Prot

Q9JJP2

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

501-631/631

Target

P73

Clonality

Polyclonal

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from mouse Tp73 protein

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1ug/ul

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

22062

Isotype

IgG

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