FAM134B Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720) . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720) . Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720) .

Synonyms

JK1; JK-1; Reticulophagy receptor FAM134B; FAM134B

Gene ID

54463

Swiss Prot

Q9H6L5

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

210-310/497

Target

FAM134B

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human FAM134B

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

There is a chance that this protein will cross-react with MSL2 based on a 73% non-sequential sequence similarity.

Prediction Reactivity

Cow, Rabbit

Gene ID URL

54463

Isotype

IgG

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