FAM134B Polyclonal Antibody
Product Specifications
Background
Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720) . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720) . Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720) .
Synonyms
JK1; JK-1; Reticulophagy receptor FAM134B; FAM134B
Gene ID
54463
Swiss Prot
Q9H6L5
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
210-310/497
Target
FAM134B
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human FAM134B
Applications
WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Specificity
There is a chance that this protein will cross-react with MSL2 based on a 73% non-sequential sequence similarity.
Prediction Reactivity
Cow, Rabbit
Gene ID URL
54463
Isotype
IgG
Curated Selection
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