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GDF8 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer; [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

Synonyms

GDF8; MSLHP; Growth/differentiation factor 8; GDF-8; Myostatin; MSTN

Gene ID

2660

Swiss Prot

O14793

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

281-375/375

Target

GDF8

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human GDF8

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Cow, Sheep, Pig, Horse, Chicken

Gene ID URL

2660

Isotype

IgG

Curated Selection

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