PELI3 Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.

Synonyms

E3 ubiquitin-protein ligase pellino homolog 3; PELI3; Pellino-3; RING-type E3 ubiquitin transferase pellino homolog 3

Gene ID

246330

Swiss Prot

Q8N2H9

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

301-400/468

Target

PELI3

Clonality

Polyclonal

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human PELI3

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1ug/ul

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Gene ID URL

246330

Isotype

IgG

Curated Selection

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