PELI3 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
Synonyms
E3 ubiquitin-protein ligase pellino homolog 3; PELI3; Pellino-3; RING-type E3 ubiquitin transferase pellino homolog 3
Gene ID
246330
Swiss Prot
Q8N2H9
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
301-400/468
Target
PELI3
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human PELI3
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Prediction Reactivity
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit
Gene ID URL
246330
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items