PELI3 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
Synonyms
E3 ubiquitin-protein ligase pellino homolog 3; PELI3; Pellino-3; RING-type E3 ubiquitin transferase pellino homolog 3
Gene ID
246330
Swiss Prot
Q8N2H9
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
301-400/468
Target
PELI3
Clonality
Polyclonal
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human PELI3
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit
Gene ID URL
246330
Isotype
IgG
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