α-Tocotrienol

α-Tocotrienol is an isoform of vitamin E and found in vegetables, fruits, seeds, nuts, grains, and oils. Vitamin E plays a role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.

Product Specifications

CAS Number

[58864-81-6]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/α-tocotrienol.html

Concentration

10mM

Purity

98.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C(C)C(C)=C2C(CC[C@](CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(C)O2)=C1C

Molecular Formula

C29H44O2

Molecular Weight

424.66

Precautions

H302, H312, H332

References & Citations

[1]Miyazawa T, et al., Anti-angiogenic potential of tocotrienol in vitro. Biochemistry (Mosc) . 2004 Jan;69 (1) :67-9.|[2]Noguchi N, et al., Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants. Free Radic Biol Med. 2003 Jun 15;34 (12) :1614-20.