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TPM2 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.

Synonyms

Tropomyosin beta chain; Beta-tropomyosin; Tropomyosin-2; TPM2; TMSB; DA1A; DA2B; NEM4; AMCD1; HEL-S-273

Gene ID

7169

Swiss Prot

P07951

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

11-130/284

Target

TPM2

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human TPM2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Rat, Dog, Cow, Chicken, Rabbit

Gene ID URL

7169

Isotype

IgG

Curated Selection

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