Phospho-Caseine Kinase 1 alpha (Tyr294) Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.

Synonyms

Casein Kinase 1 alpha phospho Y294; p-CK1A phospho Y294; Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975.

Gene ID

1452

Modification Site

Tyr294

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-Caseine Kinase 1 alpha (Tyr294)

Clonality

Polyclonal

Conjugation

Source

KLH conjugated synthetic phosphopeptide derived from human Casein Kinase 1 alpha around the phosphorylation site of Tyr294

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Sheep, Chicken, Rabbit

Gene ID URL

1452

Isotype

IgG

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