Phospho-Caseine Kinase 1 alpha (Tyr294) Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
Synonyms
Casein Kinase 1 alpha phospho Y294; p-CK1A phospho Y294; Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975.
Gene ID
1452
Modification Site
Tyr294
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Phospho-Caseine Kinase 1 alpha (Tyr294)
Clonality
Polyclonal
Conjugation
Cy3
Source
KLH conjugated synthetic phosphopeptide derived from human Casein Kinase 1 alpha around the phosphorylation site of Tyr294
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Sheep, Chicken, Rabbit
Gene ID URL
1452
Isotype
IgG
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