Phospho-Serine Polyclonal Antibody
Product Specifications
Background
Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated protein/peptides, antibodies against the phosphospecific amino acid, are important tools to explore the activation of serine, threonine or tyrosine containing proteins. An aberrant protein phosphorylation is a hallmark of human disease, and the enzymes, particularly protein kinases, which control protein phosphorylation are recognized as a major new drug target family.
Synonyms
Ser; pS; p-S; pSER; p-SER.
Modification Site
Phosphoserine
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Target
Phospho-Serine
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Phosphoserine-KLH
Applications
WB, ELISA, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Rat, Dog, Cow, Chicken, Monkey, Goose
Isotype
IgG
Curated Selection
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