SCARB1/Scavenger Receptor BI Polyclonal Antibody
Product Specifications
Background
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity) .
Synonyms
CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; Scavenger receptor class B member 1; CD36 and LIMPII analogous 1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; CD36; SCARB1
Gene ID
949
Swiss Prot
Q8WTV0
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
21-100/552
Target
SCARB1/Scavenger Receptor BI
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CD36L1
Applications
WB, ELISA, FCM, IHC-P
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Rat, Cow, Pig, Horse, Chicken, Rabbit
Gene ID URL
949
Isotype
IgG
Curated Selection
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