CDKN2A/p19ARF Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Synonyms
Arf; Alternative reading frame; smARF; p19ARF; p19; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2; Cyclin-dependent kinase 4 inhibitor A; Tumor suppressor ARF; Cdkn2a
Gene ID
12578
Swiss Prot
Q64364
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
65-169/169
Target
CDKN2A/p19ARF
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from mouse CDKN2A/p19ARF
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Prediction Reactivity
Mouse
Gene ID URL
12578
Isotype
IgG
Curated Selection
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