CDKN2A/p19ARF Polyclonal Antibody

Product Specifications

Background

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Synonyms

Arf; Alternative reading frame; smARF; p19ARF; p19; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2; Cyclin-dependent kinase 4 inhibitor A; Tumor suppressor ARF; Cdkn2a

Gene ID

12578

Swiss Prot

Q64364

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

65-169/169

Target

CDKN2A/p19ARF

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from mouse CDKN2A/p19ARF

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Mouse

Gene ID URL

12578

Isotype

IgG

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