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SOX4 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Synonyms

SOX4; SOX 4; SOX-4; Ecotropic viral integration site 16; EVI 16; EVI16; SRY sex determining region Y box 4; SRY box containing gene 4; SRY related HMG box gene 4.

Gene ID

6659

Swiss Prot

Q06945

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

54-103/474

Target

SOX4

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human SOX4

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Chicken

Gene ID URL

6659

Isotype

IgG

Curated Selection

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