E cadherin Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Synonyms
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12/8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
Gene ID
999
Swiss Prot
P12830
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
401-500/882
Target
E cadherin
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human E-cadherin
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Cow, Pig, Horse, Rabbit
Gene ID URL
999
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
134688-ML490 100 µL
Transportin-1 (Importin beta-2, Karyopherin beta-2, M9 Region Interaction Protein, MIP, TNPO1, KPNB2, MIP1, TRN) (MaxLight 490)
Ask
View Details ![Mouse Monoclonal Pentraxin 3/TSG-14 Antibody (MM0512-6B7) [Alexa Fluor 647]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-11849AF647 0.1 mL
Mouse Monoclonal Pentraxin 3/TSG-14 Antibody (MM0512-6B7) [Alexa Fluor 647]
Ask
View Details 