Z-Ala-Ala-Asp-CMK
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer[1][2].
Product Specifications
CAS Number
183284-21-1
Product Name Alternative
Z-AAD-CMK
UNSPSC
12352209
Target
Apoptosis; Caspase; Interleukin Related; Reactive Oxygen Species (ROS)
Type
Peptides
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/z-ala-ala-asp-cmk.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(CCl)=O)=O)=O
Molecular Formula
C19H24ClN3O7
Molecular Weight
441.86
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Caspase 3
Available Sizes
Frequently Asked Questions
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