Anabaseine
Product Specifications
UNSPSC Description
Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes[1][2]. Anabaseine is also a weak partial agonist at α4β2 nAChRs[3].
Target Antigen
nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anabaseine.html
Purity
96.0
Solubility
H2O : ≥ 200 mg/mL
Smiles
C1(C2=CC=CN=C2)=NCCCC1
Molecular Weight
160.22
References & Citations
[1]Kem W, et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties. Mar Drugs. 2006;4(3):255-273.|[2]Summers KL et al. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Jpn J Pharmacol. 1997 Jun;74(2):139-46.|[3]Andrud K, et al. Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine. Mar Drugs. 2019;17(11):614. Published 2019 Oct 29.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115766/Anabaseine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115766/Anabaseine-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
3471-05-4
Available Sizes
Curated Selection
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