RANKL/CD254 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Synonyms
ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; Osteoprotegerin ligand; Receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine; TNFSF11
Gene ID
8600
Swiss Prot
O14788
Cellular Locus
Cytoplasm, Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
210-317/317
Target
RANKL/CD254
Clonality
Polyclonal
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human RANKL
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat, Dog
Gene ID URL
8600
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680977-100 1x 100 µL
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040977-100 1x 100 µL
TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402147-100 1x 100 µL
Cytokeratin, Basic (Type II or HMW) (KRTH/2147R), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680791-100 1x 100 µL
Smooth Muscle Actin (ACTA2/791), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470848-500 1x 500 µL
CD31 / PECAM-1 (C31.10), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details