ITGB2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

Synonyms

LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; ITGB2

Gene ID

3689

Swiss Prot

P05107

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

701-770/770

Target

ITGB2

Clonality

Polyclonal

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Integrin beta 2

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Prediction Reactivity

Human, Mouse, Cow, Sheep, Pig, Horse

Gene ID URL

3689

Isotype

IgG

More Discoveries

Explore Other Products

Browse additional items from our catalog

NBP3-27977MFV610 0.1 mL

Human Monoclonal Histone H1 Antibody (derlotuximab) [mFluor Violet 610 SE]

View Details

TA385231 100 µL

SAP155 (SF3B1) Rabbit Monoclonal Antibody [Clone ID: R08-6I2]

View Details

NBP3-08504AF594 100 µL

Mouse Monoclonal ATG5 Antibody (ATG5/2101) [Alexa Fluor 594]

View Details

GTR15094212 1 Vial

Lentiviral human CAPN6 shRNA (UAS) - Lentiviral human CAPN6 shRNA (UAS, RFP) (100)

View Details

MBS1432351-01 0.02 mg (E-Coli)

Recombinant Staphylococcus aureus Imidazoleglycerol-phosphate dehydratase (hisB)

View Details

MBS1432351-02 0.1 mg (E-Coli)

Recombinant Staphylococcus aureus Imidazoleglycerol-phosphate dehydratase (hisB)

View Details