RGS2 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.

Synonyms

GS8; Regulator of G-protein signaling 2; RGS2; Cell growth-inhibiting gene 31 protein; G/G1 switch regulatory protein 8; GIG31

Gene ID

5997

Swiss Prot

P41220

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

116-211/211

Target

RGS2

Clonality

Polyclonal

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human RGS2

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1ug/ul

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Cow, Sheep, Pig, Horse, Chicken

Gene ID URL

5997

Isotype

IgG

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