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TIMP-3 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Synonyms

SFD; K222; K222TA2; HSMRK222; Metalloproteinase inhibitor 3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP-3; TIMP3

Gene ID

7078

Swiss Prot

P35625

Cellular Locus

Secreted, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human

Immunogen

151-211/211

Target

TIMP-3

Clonality

Polyclonal

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human TIMP-3

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Cow, Pig, Horse, Rabbit

Gene ID URL

7078

Isotype

IgG

Curated Selection

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