FGL2 Polyclonal Antibody

Product Specifications

Background

FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED) . The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

Synonyms

Fibroleukin; Cytotoxic T-lymphocyte-specic protein; Fibrinogen-like protein 2; Fibrinogen like protein 2; Prothrombinase; Fibroleukin; pT49; T49; G3V7P2_RAT, Fibrinogen-like 2.

Gene ID

84586

Swiss Prot

G3V7P2

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Rat

Immunogen

75-150/422

Target

FGL2

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from rat FGL2

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)