Caspase-1 P10 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.
Synonyms
ICE; P45; IL1BC; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; IL-1 beta-converting enzyme; CASP1; IL1BCE
Gene ID
834
Swiss Prot
P29466
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
320-404/404
Target
Caspase-1 P10
Clonality
Polyclonal
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Caspase-1
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
834
Isotype
IgG
Curated Selection
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