Caspase-1 P10 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.

Synonyms

ICE; P45; IL1BC; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; IL-1 beta-converting enzyme; CASP1; IL1BCE

Gene ID

834

Swiss Prot

P29466

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

320-404/404

Target

Caspase-1 P10

Clonality

Polyclonal

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Caspase-1

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

834

Isotype

IgG

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