GTP cyclohydrolase 1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

Synonyms

GTP-CH-1; DYT 5; DYT5; GCH 1; GCH; GCH1; GTP CH 1; GTP CH I; GTP cyclohydrolase 1 dopa responsive dystonia; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTPCH 1; GTPCH1; Guanosine 5' triphosphate cyclohydrolase I.

Gene ID

2643

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

34-110/250

Target

GTP cyclohydrolase 1

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human GTP-CH-1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Rat

Gene ID URL

2643

Isotype

IgG

More Discoveries

Explore Other Products

Browse additional items from our catalog

AE30387RA-01 48 Tests

Rat Nuclear receptor subfamily 4 group A member 2 (NR4A2) ELISA Kit

View Details

AE30387RA-02 96 Tests

Rat Nuclear receptor subfamily 4 group A member 2 (NR4A2) ELISA Kit

View Details

GC4129-1g 1 g

Benzyl β-D-erythrofuranoside

View Details

NBP2-99883APC 0.1 mL

Rabbit Polyclonal CD300c Antibody [Allophycocyanin]

View Details

MBS157360-01 0.05 mg

Recombinant Salmonella phage SFP10 SFP_0162 protein, N-His tag

View Details

MBS157360-02 0.1 mg

Recombinant Salmonella phage SFP10 SFP_0162 protein, N-His tag

View Details