AKT1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Selected Variant
bs-0115R-BF750-TR
Size: 20 µL
Product Specifications
Background
AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
Synonyms
AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; Protein kinase B; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2; PKBG
Gene ID
207
Swiss Prot
P31749
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Pig
Immunogen
401-479/479
Target
AKT1
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human AKT1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Dog, Cow, Sheep, Chicken, Rabbit
Gene ID URL
207
Isotype
IgG
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUM2791-50 1x 50 µL
Cathepsin K (Marker of Tumor Invasiveness) (CTSK/2791), 1mg/mL
Sign In for Pricing
View Details 
BNC402145-500 1x 500 µL
CD61 / Integrin 3 / Platelet Glycoprotein IIIa (Platelet Marker) (ITGB3/2145), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB1879-500 1x 500 µL
Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (rBCL2/796), 0.2mg/mL
Sign In for Pricing
View Details 
BNC473089-100 1x 100 µL
MSH6 (DNA Mismatch Repair Protein) (MSH6/3089), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940719-500 1x 500 µL
Mitochondrial Marker (MTC719), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details