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Progesterone Receptor Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Synonyms

PR; NR3C3; Progesterone receptor; Nuclear receptor subfamily 3 group C member 3; PGR

Gene ID

5241

Swiss Prot

P06401

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

501-600/933

Target

Progesterone Receptor

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human progesterone receptor

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Dog, Pig, Horse, Rabbit

Gene ID URL

5241

Isotype

IgG

Curated Selection

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