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Leptin Receptor Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Receptor for obesity factor (leptin) . On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity) .

Synonyms

OBR; OB-R; CD295; LEP-R; LEPRD; Leptin receptor; HuB219; OB receptor; LEPR; DB; LEPR_MOUSE

Gene ID

3953

Swiss Prot

P48357

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

901-1000/1165

Target

Leptin receptor (Isoform B)

Clonality

Polyclonal

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Specificity

This antibody will recognize the Isoform B variant only

Prediction Reactivity

Dog, Cow, Sheep, Pig

Gene ID URL

3953

Isotype

IgG

Curated Selection

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