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Secretin Polyclonal Antibody

Product Specifications

Background

Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.

Synonyms

SCT; Secretin precursor; SECR_HUMAN; Secr.

Gene ID

6343

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

28-54/121

Target

Secretin

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Secretin

Applications

WB, ELISA, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Human, Pig

Gene ID URL

6343

Isotype

IgG

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