APAF1 (CT) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Synonyms
CED4; APAF-1; Apoptotic protease-activating factor 1; APAF1; KIAA0413
Gene ID
317
Swiss Prot
O14727
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
1201-1248/1248
Target
APAF1 (CT)
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human Apaf-1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Dog, Horse
Gene ID URL
317
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
I7662-13D-APC 100 µL
IRS-p53 (Insulin Receptor Substrate p53, BAIAPC2, Brain-enriched scaffolding protein) (APC)
Ask
View Details 
MBS1251433-01 1 mg (E-Coli)
Recombinant Saccharomyces cerevisiae Protein SCO2, mitochondrial (SCO2) , partial
Ask
View Details 
MBS1251433-02 1 mg (Yeast)
Recombinant Saccharomyces cerevisiae Protein SCO2, mitochondrial (SCO2) , partial
Ask
View Details