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APAF1 (CT) Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Synonyms

CED4; APAF-1; Apoptotic protease-activating factor 1; APAF1; KIAA0413

Gene ID

317

Swiss Prot

O14727

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

1201-1248/1248

Target

APAF1 (CT)

Clonality

Polyclonal

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human Apaf-1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Dog, Horse

Gene ID URL

317

Isotype

IgG

Curated Selection

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