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BTG2 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1 (referenced from Entrez Gene) . BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF) ; suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398) .

Synonyms

BTG2_HUMAN; Protein BTG2; BTG family member 2; NGF-inducible anti-prolerative protein PC3; pheochromacytoma cell-3; nerve growth factor-inducible anti-prolerative; B-cell translocation gene 2; BTG2; TIS21; PC3; TIS21.

Gene ID

7832

Swiss Prot

P78543

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

31-110/158

Target

BTG2

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human BTG2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Rat, Pig, Rabbit, GuineaPig

Gene ID URL

7832

Isotype

IgG

Curated Selection

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