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IGF2 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

Synonyms

IGF-II; PP9974; C11orf43; Insulin-like growth factor II; Somatomedin-A; IGF2; PP1446

Gene ID

3481

Swiss Prot

P01344

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

25-51/180

Target

IGF2

Clonality

Polyclonal

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human IGF II

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Dog, Cow, Sheep, Pig, Rabbit

Gene ID URL

3481

Isotype

IgG

Curated Selection

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