Tubulin inhibitor 30
Selected Variant
HY-151879-01
Size: 5 mg
Tubulin inhibitor 30 (Compound 15) is a tubulin assembly inhibitor with an IC50 of 0.52 μM. Tubulin inhibitor 30 can induce ferroptosis[1].
Product Specifications
CAS Number
2873383-67-4
UNSPSC
12352005
Target
Ferroptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-30.html
Purity
99.77
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=CC(C(C2=CN(C=C2C3=CC=CO3)C4=NC=CC=N4)=O)=CC(OC)=C1OC
Molecular Formula
C22H19N3O5
Molecular Weight
405.40
References & Citations
[1]Puxeddu M, et al. Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor. J Med Chem. 2022 Nov 17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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