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Mouse ox-LDL, Biotin Conjugated

Product Specifications

Background

Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

Expression System

Native protein

Conjugation

Biotin

Source

Purified native protein

Applications

Others

Endotoxin

Not Tested

Purity

>95% as determined by SDS-PAGE

Buffer

Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4) . 5% trehalose is added as a protectant before lyophilization.

Storage Conditions

The product should be stored at -70°C or -20°C.

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