Recombinant human RANK protein, C-His (HEK293)
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Gene ID
8792
Swiss Prot
Q9Y6Q6
Expression System
HEK293
Conjugation
Unconjugated
Tag
C-His
Source
Recombinant human RANK protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 30-212/616
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
0.01M TBS (pH7.4)
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
8792
Available Sizes
Curated Selection
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