Recombinant human IL-13, His (HEK293), APC Conjugated
Product Specifications
Background
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Gene ID
16163
Swiss Prot
P20109
Expression System
HEK293
Conjugation
APC
Tag
C-His
Source
Recombinant human IL-13 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 25-146/146
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Species
Others
Gene ID URL
16163
Available Sizes
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